Try Our ReliaBLOT Western Blot Kits | Bethyl Laboratories | THE LINK | March 2012

Having trouble viewing this email? Click here.
To ensure you receive Bethyl Laboratories emails, please add newsletter@bethyl.com to your address book

The Wnt Signaling Pathway. Contributed by Kevin P. Roarty, Ph.D. The Wnt pathway comprises a family of cysteine-rich glycoproteins that are highly conserved between multiple animal species and are necessary for nearly every facet of embryonic development, adult tissue homeostasis, and stem cell dynamics (1). Originally identified in 1982 as the favored site of integration by the Mouse Mammary Tumor Virus (MMTV) in viral-induced mammary tumorigenesis, the gene int-1 (now wnt-1) was later recognized as the homolog to the Drosophila fly wingless gene (2). To date, 19 Wnt ligands and 10 Frizzled receptors have been identified in mice and humans, eliciting an intricate web of downstream signals. These outputs are categorized by their ability to mediate a β-catenin-dependent (canonical) or β-catenin-independent (noncanonical) response. READ MORE - http://www.bethyl.com/content/bulletin_Wnt

The ReliaBLOT Western Blot Kits conveniently provide the major reagents needed to perform five standard western blot assays.
The kits include:
- Precast SDS-PAGE Gel Cassettes (5X)
- LDS Buffer (4X)
- DTT Reducing Agent (10X)
- Prestained Protein Marker
- Running Buffer (20X)
- Transfer Buffer (10X)
- Nitrocellulose Membrane Filter Sandwiches (7.5 x 8.3 cm)
- HRP-Conjugated Anti-Rabbit Secondary Antibody
- Chemiluminescent HRP Substrate

Description Price (Per Kit)
ReliaBLOT WB Kit, 4-8%, 10 x 10 cm $250
ReliaBLOT WB Kit, 4-12%, 10 x 10 cm $250
ReliaBLOT WB Kit, 4-20%, 10 x 10 cm $250
ReliaBLOT WB Kit, 12%, 10 x 10 cm $250
ReliaBLOT WB Kit, 4-8%, 10 x 8 cm $250
ReliaBLOT WB Kit, 4-12%, 10 x 8 cm $250
ReliaBLOT WB Kit, 4-20%, 10 x 8 cm $250
ReliaBLOT WB Kit, 12%, 10 x 8 cm $250

View all ReliaBLOT Products
http://www.bethyl.com/category/pca_accessory_reliablot

A Body of Work.
Stay up-to-date with current industry information by reading this month's featured article.
Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase - Transcription
Yuan-Chin Tsai, Todd M. Greco, Apaporn Boonmee, Yana Miteva, and Ileana M. Cristea

VIEW ABSTRACT - http://www.mcponline.org/content/11/2/M111.015156.abstract

A Beacon of Trust.
In conjunction with our eNewsletter, we're also unveiling The Bethyl Laboratories Seal which certifies that our antibodies are 100% manufactured and qualified to the highest standards at our sole facility in Texas.

Come See Us.
We will be exhibiting at the 2012 American Association for Cancer Research (AACR) Annual Meeting, April 1 – April 4 at McCormick Place in Chicago, Illinois. Stop by and see us at booth #1142 to receive a FREE t-shirt*
*While supplies last.

New Products.
Each month, we will release a series of new antibodies. For a complete listing of products, click on the button below.

NEW ANTIBODIES - http://www.bethyl.com/content/new_products