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vPARP Antibody

PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD+ as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis.vPARP is also known as PARP-related IalphaI-related H5/proline-rich, PH5P, p193, PARPL, VWA5C, VAULT3, ADPRTL1, and KIAA0777.

Product / Catalog #	Specifications	Price
vPARP Antibody A301-953A	Applications: IP Reactivity: Human Quantity: 0.1 ml	$280.00 Data Sheet Add to Cart
vPARP Antibody A301-954A	Applications: WB, IP Reactivity: Human Quantity: 0.1 ml (20 - 100 blots)	$280.00 Data Sheet Add to Cart
vPARP Antibody AbVantage™ Pack A310-691A	Applications: WB, IP Reactivity: Human Quantity: 1 each of A301-953A and A301-954A	$390.00 Data Sheet Add to Cart
vPARP Blocking Peptide BP301-953	Applications: Blocks A301-953A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart
vPARP Blocking Peptide BP301-954	Applications: Blocks A301-954A Quantity: 50 mcg	$115.00 Data Sheet Add to Cart

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