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vPARP
vPARP Antibody
PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD+ as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis. vPARP is also known as PARP-related IalphaI-related H5/proline-rich, PH5P, p193, PARPL, VWA5C, VAULT3, ADPRTL1, and KIAA0777.
Product / Catalog #
Specifications
Price
vPARP Antibody
A301-953A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
vPARP Antibody
A301-954A
Applications:
WB, IP
Reactivity:
Human
Quantity:
0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
vPARP Antibody AbVantage™ Pack
A310-691A
Applications:
WB, IP
Reactivity:
Human
Quantity:
1 each of A301-953A and A301-954A
$390.00
Data Sheet
Add to Cart
vPARP Blocking Peptide
BP301-953
Applications:
Blocks A301-953A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
vPARP Blocking Peptide
BP301-954
Applications:
Blocks A301-954A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
Product Focuses
ATM and ATR Signaling Proteins
Condensin Complex
GTPase Regulation
mTOR Signaling Pathway
NFKB
Nucleoporin
SWI/SNF
USP
WD-repeat
Xeroderma Pigmentosum
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Bethyl Laboratories, Inc.
P.O. Box 850
Montgomery, TX 77356
Phone: 1-800-338-9579
Fax: 1-866-597-6105