vPARP Antibody

PARP4 [poly(ADP-ribose) polymerase family, member 4] catalyzes the formation of ADP-ribose polymers covalently attached to proteins using NAD+ as a substrate. There are 6 mammalian PARP enzymes: PARP1, PARP2, PARP3, PARP4/vPARP, PARP5/Tankyrase-1, and PARP6/Tankyrase-2. PARP4 is also known as vault PARP (vPARP) due to its association with the vault particle, a 13MDa cytoplasmic ribonucleoprotein complex whose barrel-shaped structure resembles arched cathedral ceilings. vPARP has also been identified separate from the vault particle. It has been localized to the nuclear pore, mitotic spindle, and cytoplasm. It also has been shown to associate with telomerase activity. Studies of vPARP knockout mice show an increased susceptibility to carcinogen-induced tumorigenesis.
    Product Specifications
    Catalog # Size Price
    vPARP AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1400 and 1450
    A301-953A100 µl (1 mg/ml) $339Add to Cart
    A301-953A-T10 µl (1 mg/ml) $50Add to Cart
    vPARP AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1674 to 1724
    A301-954A100 µl (0.2 mg/ml) $339Add to Cart
    A301-954A-M100 µl (10 blots) $229Add to Cart
    A301-954A-T20 µl (2 blots) $50Add to Cart
    vPARP IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 1674 and 1724
    IHC-00580100 µl (50+ slides) $360Add to Cart
    IHC-00580-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A301-953A and A301-954A
    A310-691A1 Pack $472Add to Cart

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