p600 Antibody

p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T4S7].
    Product/Catalog #SpecificationsPrice
    p600 Antibody
    A302-277A
    Reactivity: Human
    Applications: IP, IHC-P, IF
    $314.00
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    p600 Antibody
    A302-278A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    $314.00
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    p600 Antibody
    A302-279A
    Reactivity: Human
    Applications: WB, IHC-P, IF
    $314.00
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    p600 Antibody AbVantage™ Pack
    A310-822A
    Applications: WB, IP
    Reactivity: Human
    Quantity: 1 each of A302-277A, A302-278A and A302-279A
    $653.00
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    p600 IHC Antibody
    IHC-00640
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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