p400 belongs to the SWI2/SNF2 family of chromatin remodeling proteins and is a component of the NuA4 histone acetyltransferase complex. In this complex p400 positively regulates transcription by modifying nucleosome structure. P400 has also been found to play a role in the p52-p21 pathway that regulates p21 transcription and senescence as well as the ARF-p53 pathway that couples cell proliferation to apoptosis.
Alternative names for
p400 Antibody include EP400 antibody, E1A binding protein p400 antibody, TNRC12 antibody, TNRC-12 antibody, trinucleotide repeat containing 12 antibody, CAGH32 protein antibody, Domino homolog antibody, hDomino antibody, KIAA1498 antibody, KIAA1818 antibody, FLJ42018 antibody, FLJ45115 antibody, TNRC12 antibody.