p400 belongs to the SWI2/SNF2 family of chromatin remodeling proteins and is a component of the NuA4 histone acetyltransferase complex. In this complex p400 positively regulates transcription by modifying nucleosome structure. P400 has also been found to play a role in the p52-p21 pathway that regulates p21 transcription and senescence as well as the ARF-p53 pathway that couples cell proliferation to apoptosis.
Alternative names for
p400 Antibody include Domino homolog antibody,
domino homolog antibody,
CAG repeat protein 32 antibody,
Trinucleotide repeat-containing gene 12 protein antibody,
p400 kDa SWI2/SNF2-related protein antibody,
E1A binding protein
p400 SWI2/SNF2-related protein antibody,
trinucleotide repeat containing 12 antibody,
trinucleotide repeat-containing gene 12 protein antibody.