eIF3G/EIF3S4 Antibody

Eukaryotic initiation factor 3 subunit G (eIF3G) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3G has been shown to directly interact with AIF (apoptosis inducing factor), a protein that plays a role in caspase-independent apoptosis. AIF is able to inhibit protein synthesis via its interaction with eIF3g.

Alternative names for eIF3G/EIF3S4 Antibody include eukaryotic translation initiation factor 3 subunit 4 antibody, EIF3S4 antibody, eIF3delta antibody, eIF3 RNA binding subunit antibody, eIF p44 antibody, eIF p42 antibody.