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cAbl
cAbl Antibody
c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias. Alternate names for c-Abl include proto-oncogene tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, p150, ABL1, ABL, and JTK7.
Product / Catalog #
Specifications
Price
cAbl Antibody
A301-660A
Applications:
WB, IP
Reactivity:
Human
Quantity:
0.1 ml (20 - 100 blots)
$280.00
Data Sheet
Add to Cart
cAbl Antibody
A301-661A
Applications:
IP
Reactivity:
Human
Quantity:
0.1 ml
$280.00
Data Sheet
Add to Cart
cAbl Antibody AbVantage™ Pack
A310-589A
Applications:
WB, IP
Reactivity:
Human
Quantity:
1 each of A301-660A and A301-661A
$390.00
Data Sheet
Add to Cart
cAbl IHC Antibody
IHC-00405
Applications:
IHC
Reactivity:
Human
Quantity:
0.1 ml (50 - 250 slides)
$360.00
Data Sheet
Add to Cart
cAbl Blocking Peptide
BP301-660
Applications:
Blocks A301-660A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
cAbl Blocking Peptide
BP301-661
Applications:
Blocks A301-661A
Quantity:
50 mcg
$115.00
Data Sheet
Add to Cart
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Montgomery, TX 77356
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