ZNF198 contains nine MYM-type zinc fingers. The N-terminal half of the ZNF198 gene has been identified as a gene fused to the cytoplasmic domain of the fibroblast growth factor receptor (FGFR1) gene as a result of a t(8;13) (p11;q11-12) chromosomal rearrangement. The t(8;13) chromosomal translocation is associated with myeloproliferative diseases such as stem cell leukemia lymphoma syndrome (SCLL). Studies of the normal function of ZNF198 have revealed that it associates with HHR6 and RAD18 and may be involved in the repair of DNA. ZNF198 has also been found to associate with the BHC110 subunit of a histone-deacetylase containing corepressor complex and may have an additional function in transcriptional repression.
Alternative names for
ZNF198 Antibody include ZMYM2 antibody,
Zinc finger MYM-type protein 2 antibody,
Fused in myeloproliferative disorders protein antibody,
Rearranged in atypical myeloproliferative disorder protein antibody,
Zinc finger protein 198 antibody,
zinc finger, MYM-type 2 antibody,
zinc finger MYM-type protein 2 antibody,
zinc finger protein 198 antibody,
fused in myeloproliferative disorders protein antibody,
rearranged in an atypical myeloproliferative disorder antibody.