ZEB1 Antibody

ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.
    Product Specifications
    Catalog # Size Price
    ZEB1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 850 and 900
    A301-921A100 µl (0.2 mg/ml) $339Add to Cart
    A301-921A-M100 µl (10 blots) $229Add to Cart
    A301-921A-T20 µl (2 blots) $50Add to Cart
    ZEB1 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1074 and 1124
    A301-922A100 µl (0.2 mg/ml) $339Add to Cart
    A301-922A-M100 µl (10 blots) $229Add to Cart
    A301-922A-T20 µl (2 blots) $50Add to Cart
    ZEB1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 1074 and 1124
    IHC-00419100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A301-921A and A301-922A
    A310-681A1 Pack $472Add to Cart

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