XPE/DDB1 Antibody

DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.
    Product Specifications
    Catalog # Size Price
    DDB1 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 1100 and C-term
    A300-462A100 µl (0.2 mg/ml) $339Add to Cart
    A300-462A-M100 µl (10 blots) $229Add to Cart
    A300-462A-T20 µl (2 blots) $50Add to Cart

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