WD-repeat domain 5 (WDR5) is a member of the WD repeat family. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WDR5 contains 7 WD repeats and is a core subunit of the human MLL and SET1 histone H3 lys4 methyltransferase complexes. WDR5 functions in facilitating the assembly of MLL and SET1 chromatin-modifiying complexes.
Alternative names for
WDR5 Antibody include
WD repeat-containing protein 5 antibody,
BMP2-induced 3-kb gene protein antibody,
WD repeat domain 5 antibody,
WD-repeat protein 5 antibody,
SWD3, Set1c WD40 repeat protein, homolog antibody.