WDFY3 Antibody

WDFY3 ( WD repeat and FYVE domain –containing protein 3) was identified in a screen for phosphatidylinositol -3-phosphate [PtdIns(3)P]- binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns(3)-binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery.

Alternative names for WDFY3 Antibody include autophagy-linked FYVE protein (Alfy) antibody.