Ubinuclein-1 acts as a novel regulator of senescence. It is involved in the formation of senescence-associated heterochromatin foci (SAHF), which repress expression of proliferation-promoting genes. Ubinuclein-1 binds to proliferation-promoting genes and may be required for replication-independent chromatin assembly.
Alternative names for
Ubinuclein-1 Antibody include ubiquitously expressed nuclear protein antibody, HIRA-binding protein antibody, protein VT4 antibody, UBN1 antibody.