The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 48 (USP48) is a member of the C19 peptidase family involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. USP48 is involved in the activation of NF-kappa B via its interaction with RELA and TRAF2.
Alternative names for
USP48 Antibody include ubiquitin carboxyl-terminal hydrolase 48 antibody, ubiquitin thioesterase 48 antibody, ubiquitin-specific-processing protease 48 antibody, deubiquitinating enzyme 48 antibody, USP31 antibody, RAP1GA1 antibody.