USP1 Antibody

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 1 (USP1) has been found to play a role in the Fanconi anemia DNA repair pathway. USP1 specifically removes monoubiquitination from the Fanconi anemia D2 (FANCD2) protein and from the proliferating cell nuclear antigen (PCNA). Deubiquitination of FANCD2 and PCNA is critical to their role in the DNA damage response and DNA crosslink repair.
    Product Specifications
    Catalog # Size Price
    USP1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 300 and 350
    A301-698A100 µl (1 mg/ml) $339Add to Cart
    A301-698A-T10 µl (1 mg/ml) $50Add to Cart
    USP1 AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 450 and 500
    A301-699A100 µl (1 mg/ml) $339Add to Cart
    A301-699A-T10 µl (1 mg/ml) $50Add to Cart
    USP1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 584 and 634
    A301-700A100 µl (1 mg/ml) $339Add to Cart
    A301-700A-T10 µl (1 mg/ml) $50Add to Cart
    USP1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 450 and 500
    IHC-00391100 µl (50 slides) $360Add to Cart
    Applications: IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A301-698A, A301-699A and A301-700A
    A310-602A1 Pack $707Add to Cart

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