USP1 Antibody

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 1 (USP1) has been found to play a role in the Fanconi anemia DNA repair pathway. USP1 specifically removes monoubiquitination from the Fanconi anemia D2 (FANCD2) protein and from the proliferating cell nuclear antigen (PCNA). Deubiquitination of FANCD2 and PCNA is critical to their role in the DNA damage response and DNA crosslink repair.
    Product/Catalog #SpecificationsPrice
    USP1 Antibody
    A301-698A
    Reactivity: Human
    Applications: IP
    $314.00
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    USP1 Antibody
    A301-699A
    Reactivity: Human
    Applications: IP, IHC-P, IF
    $314.00
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    USP1 Antibody
    A301-700A
    Reactivity: Human
    Applications: IP
    $314.00
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    USP1 Antibody AbVantage™ Pack
    A310-602A
    Applications: IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A301-698A, A301-699A and A301-700A
    $655.00
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    USP1 IHC Antibody
    IHC-00391
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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