UFD1 Antibody

Ubiquitin fusion degradation protein 1 homolog (UFD1) forms a dimer with Npl4 (nuclear protein localization 4) and can associate with the ATPase, p97/VCP, to form a ternary complex involved in the ubiquitin-proteasome pathway. The UFD1-p97-Npl4 complex functions to recognize ubiquitin-tagged proteins and facilitate their presentation to the 26S proteasome for degradation. This ternary complex has also been shown to play an important role in mitotic spindle disassembly. Hemizygosity in the gene which encodes UFD1 (UFD1L) is the cause of some catch 22-associated developmental defects. Additionally, the UFD1L gene has also been implicated in the neurodevelopment al origin of schizophrenia.
    Product Specifications
    Catalog # Size Price
    UFD1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 175 and 225
    A301-875A100 µl (0.2 mg/ml) $339Add to Cart
    A301-875A-M100 µl (10 blots) $229Add to Cart
    A301-875A-T20 µl (2 blots) $50Add to Cart
    UFD1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 257 and 307
    A301-876A100 µl (0.2 mg/ml) $339Add to Cart
    A301-876A-M100 µl (10 blots) $229Add to Cart
    A301-876A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-875A and A301-876A
    A310-667A1 Pack $472Add to Cart

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