UBXN1 Antibody

UBX domain-containing protein 1 (UBXN1) is a ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. The interaction between UBXN1 and autoubiquitinated BRCA1, leads to the inhibition the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. UBXN1 is also a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.3 kDa protein, UBXD10, 2B28, and SAKS1.
    Product Specifications
    Catalog # Size Price
    UBXN1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 50 and 100
    A303-415A100 µl (0.2 mg/ml) $339Add to Cart
    A303-415A-M100 µl (10 blots) $229Add to Cart
    A303-415A-T20 µl (2 blots) $50Add to Cart
    UBXN1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 262 and 312
    A303-416A100 µl (1 mg/ml) $339Add to Cart
    A303-416A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A303-415A and A303-416A
    A311-260A1 Pack $472Add to Cart

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