UBR1 Antibody

UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IWV7].
    Product Specifications
    Catalog # Size Price
    UBR1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 225 and 275
    A302-987A100 µl (1 mg/ml) $339Add to Cart
    A302-987A-T10 µl (1 mg/ml) $50Add to Cart
    UBR1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1125 and 1175
    A302-988A100 µl (1 mg/ml) $339Add to Cart
    A302-988A-M100 µl (10 blots) $229Add to Cart
    A302-988A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-987A and A302-988A
    A311-108A1 Pack $472Add to Cart

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