U2AF65 Antibody

U2 auxiliary factor (U2AF) is comprised of a large and a small subunit and is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. Splicing factor U2 auxiliary factor 65 kDa subunit (U2AF65) is the large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. U2AF65 binds to the polypyrimidine tract of introns early during spliceosome assembly [taken from NCBI Entrez Gene (Gene ID: 11338)].

Alternative names for U2AF65 Antibody include U2AF2 antibody, hU2AF(65) antibody, hU2AF65 antibody, U2 snRNP auxiliary factor large subunit antibody.