U2AF35 heterodimerizes with U2AF65 to form the U2 snRNP auxiliary factor which is part of the splicesome. U2AF35 is required for splicing of AG-dependent pre-mRNAs and functions in recognizing the conserved 3’ splice site dinucleotide AG. U2AF35 contains an atypical RNA recognition motif (RRM), two C3H1-type zinc fingers, and a C-terminal arginine/serine (RS)-rich domain interrupted by glycines.
Alternative names for
U2AF35 Antibody include U2AF1 antibody,
Splicing factor U2AF 35 kDa subunit antibody,
U2 auxiliary factor 35 kDa subunit antibody,
U2 small nuclear RNA auxiliary factor 1 antibody,
U2 snRNP auxiliary factor small subunit antibody,
splicing factor U2AF 35 kDa subunit antibody,
splicing factor U2AF 35kDa subunit antibody,
U2 small nuclear RNA auxillary factor 1 antibody,
U2RNU2) small nuclear RNA auxiliary factor binding protein antibody,
U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit antibody.