Thioredoxin-interacting protein (TXNIP) may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. TXNIP interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Also, TXNIP functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H3M7].
Alternative names for
TXNIP Antibody include
Thioredoxin-interacting protein antibody,
Thioredoxin-binding protein 2 antibody,
Vitamin D3 up-regulated protein 1 antibody,
thioredoxin interacting protein antibody,
thioredoxin-interacting protein antibody,
thioredoxin binding protein 2 antibody,
thioredoxin-binding protein 2 antibody,
vitamin D3 up-regulated protein 1 antibody,
upregulated by 1,25-dihydroxyvitamin D-3 antibody.