TXNIP Antibody

Thioredoxin-interacting protein (TXNIP) may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. TXNIP interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Also, TXNIP functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H3M7].
    Product Specifications
    Catalog # Size Price
    TXNIP AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 300 and 350
    A303-229A100 µl (1 mg/ml) $339Add to Cart
    A303-229A-T10 µl (1 mg/ml) $50Add to Cart

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