Tuberous sclerosis 1 protein (TSC1) forms a heterodimer with TSC2 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb.
Alternative names for
TSC1 Antibody include Hamartin antibody,
Tuberous sclerosis 1 protein antibody,
tuberous sclerosis 1 antibody,
tumor suppressor antibody,
tuberous sclerosis 1 protein antibody.