TRPC6 (transient receptor potential cation channel, subfamily C, member 6) forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in the TRPC6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) [taken from NCBI Entrez Gene (Gene ID: 7225].
Alternative names for
TRPC6 Antibody include transient receptor protein 6 antibody, TRP-6 antibody, TrpC6 antibody.