PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.
Alternative names for
TRIM19/PML Antibody include Protein
Promyelocytic leukemia protein antibody,
RING finger protein 71 antibody,
Tripartite motif-containing protein 19 antibody,
promyelocytic leukemia antibody,
promyelocytic leukemia protein antibody,
tripartite motif protein TRIM19 antibody,
probable transcription factor
promyelocytic leukemia, inducer of antibody,
tripartite motif-containing protein 19 antibody.