TOPORS Antibody

TOPORS (topoisomerase I-binding RS protein) was identified in a a yeast two-hybrid screen for proteins that bind the N-terminus of topoisomerase I. TOPORS contains a RING-type zinc-finger domain and an RS-rich region. TOPORS has been found to possess both ubiquitin and SUMO-1 E3 ligase activity. It can ubiquitinate and sumoylate p53 and may possibly function as a tumor suppressor. Defects in TOPORS are the cause of retinitis pigmentosa type 31.
    Product Specifications
    Catalog # Size Price
    TOPORS AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 995 and 1045
    A302-179A100 µl (0.2 mg/ml) $339Add to Cart
    A302-179A-M100 µl (10 blots) $229Add to Cart
    A302-179A-T20 µl (2 blots) $50Add to Cart
    TOPORS IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 995 and 1045
    IHC-00629100 µl (50 slides) $360Add to Cart

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