TOPORS Antibody

TOPORS (topoisomerase I-binding RS protein) was identified in a a yeast two-hybrid screen for proteins that bind the N-terminus of topoisomerase I. TOPORS contains a RING-type zinc-finger domain and an RS-rich region. TOPORS has been found to possess both ubiquitin and SUMO-1 E3 ligase activity. It can ubiquitinate and sumoylate p53 and may possibly function as a tumor suppressor. Defects in TOPORS are the cause of retinitis pigmentosa type 31.
    Product/Catalog #SpecificationsPrice
    TOPORS Antibody
    A302-179A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    TOPORS IHC Antibody
    IHC-00629
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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