TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.
Alternative names for
TIF1 Alpha/TRIM24 Antibody include transcription intermediary factor 1-alpha antibody, tripartite motif-containing protein 24 antibody, RING finger protein 82 antibody, RNF82 antibody, TIF1 antibody, hTIF1 antibody, TIF1A antibody, PTC6 antibody.