TFIIIC102/GTF3C3 Antibody

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

Alternative names for TFIIIC102/GTF3C3 Antibody include general transcription factor 3C polypeptide 3 antibody, transcription factor IIIC subunit gamma antibody, TF3C-gamma antibody, TFIIIC 102 kDa subunit antibody, TFIIIC102 antibody, general transcription factor IIIC polypeptide 3 (beta subunit antibody, 102 kDa) antibody.