TDP2 Antibody

TDP2 (5’-Tyr-DNA phosphodiesterase 2) is also known as TTRAP (TRAF and TNF receptor-associated protein). TTRAP is a DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. It catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. TTRAP also hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. TTRAP may also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95551].
    Product Specifications
    Catalog # Size Price
    TDP2 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 50 and 100
    A302-737A100 µl (0.2 mg/ml) $339Add to Cart
    A302-737A-M100 µl (10 blots) $229Add to Cart
    A302-737A-T20 µl (2 blots) $50Add to Cart

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