TBP (TATA-box-binding protein) is a key component of the multiprotein transcription factor TFIID (transcription factor IID) which binds to core promoters and activates RNA polymerase II transcription. TBP is responsible for directing TFIID binding to the TATA-box to form the pre-initiation transcriptional complex. Mutations in the polyglutamine tract of TBP are associated with the neurodegenerative disorder spinocerebellar ataxia 17.
Alternative names for
TBP Antibody include TATA-box factor antibody,
TATA-box factor antibody,
TATA-box-binding protein antibody,
TATA sequence-binding protein antibody,
TATA-binding factor antibody,
Transcription initiation factor TFIID TBP subunit antibody,
TATA box binding protein antibody,
TATA-box binding protein N-terminal domain antibody,
transcription initiation factor TFIID TBP subunit antibody.