TBK1 is a member of the I-kappa-B kinase (IKK) family that plays a role in embryonic development and in the innate immune response. In response to viral infection, TBK1 activity induces transcription of genes such as IFN-gamma inducible protein (ip10), and interferon beta (ifnb). TBK1 is also implicated in the NF-kappa-B activation pathway which involves phosphorylation of I-kappaB proteins and the release and translocation of the NF-kappa-B complex to the nucleus.
Alternative names for
TBK1 Antibody include serine/threonine-protein kinas TBK1 antibody, TANK-binding kinase antibody, T2K antibody, NF-kappa-B-activating kinase antibody, NAK antibody, FLJ11330 antibody.