SuFu Antibody

Suppressor of fused (SuFu) is a negative regulator of the hedgehog and beta-catenin signaling pathway. It down-regulates GLI1-mediated transactivation of target genes and is part of a corepressor complex that acts on DNA-bound GLI1. SuFu may also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Additionally, SuFu sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UMX1].
    Product Specifications
    Catalog # Size Price
    SuFu AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 325 and 375
    A302-334A100 µl (1 mg/ml) $339Add to Cart
    A302-334A-T10 µl (1 mg/ml) $50Add to Cart
    SuFu AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 434 and 484
    A302-335A100 µl (0.2 mg/ml) $339Add to Cart
    A302-335A-M100 µl (10 blots) $229Add to Cart
    A302-335A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-334A and A302-335A
    A310-846A1 Pack $472Add to Cart

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