Sprouty 2 Antibody

Sprouty 2 contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells sprouty 2 is transiently upregulated in response to fibroblast growth factor two. Sprouty 2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. Sprouty 2 interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. Sprouty 2 may play a role in alveoli branching during lung development as shown by a similar mouse protein [taken from NCBI Entrez Gene (Gene ID: 10253)].
    Product Specifications
    Catalog # Size Price
    Sprouty 2 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 75 and 125
    A303-534A100 µl (1 mg/ml) $339Add to Cart
    A303-534A-T10 µl (1 mg/ml) $50Add to Cart
    Sprouty 2 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 265 and 315
    A303-535A100 µl (1 mg/ml) $339Add to Cart
    A303-535A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: IP
    Reactivity: Human
    Includes: 1 each of A303-534A and A303-535A
    A311-303A1 Pack $472Add to Cart

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