Sirt6 Antibody

Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N6T7].
    Product Specifications
    Catalog # Size Price
    Sirt6 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 50 and 100
    A302-451A100 µl (1 mg/ml) $339Add to Cart
    A302-451A-T10 µl (1 mg/ml) $50Add to Cart
    Sirt6 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 305 and 355
    A302-452A100 µl (1 mg/ml) $339Add to Cart
    A302-452A-M100 µl (10 blots) $229Add to Cart
    A302-452A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-451A and A302-452A
    A310-889A1 Pack $472Add to Cart

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