STUB1/CHIP Antibody

STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down’s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.
    Product Specifications
    Catalog # Size Price
    STUB1/CHIP AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 1 and 50
    A301-572A100 µl (0.2 mg/ml) $339Add to Cart
    A301-572A-M100 µl (10 blots) $229Add to Cart
    A301-572A-T20 µl (2 blots) $50Add to Cart
    STUB1/CHIP AntibodyReactivity: Human, Mouse
    Applications: IP, IHC-P, IF
    Immunogen: Between 253 and 303
    A301-573A100 µl (1 mg/ml) $339Add to Cart
    A301-573A-T10 µl (1 mg/ml) $50Add to Cart

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