STAT3 Antibody

STAT3 (signal transducer and activator of transcription 3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein [taken from NCBI Entrez Gene (GeneID:6774)].
    Product Specifications
    Catalog # Size Price
    STAT3 AntibodyReactivity: Human
    Applications: IP, PLA
    Immunogen: Between 675 and 725
    A302-405A100 µl (1 mg/ml) $339Add to Cart
    A302-405A-T10 µl (1 mg/ml) $50Add to Cart
    STAT3 AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 720 and 770
    A302-406A100 µl (1 mg/ml) $339Add to Cart
    Applications: WB, IP, PLA
    Reactivity: Human, Mouse
    Includes: 1 each of A302-405A and A302-406A
    A310-871A1 Pack $472Add to Cart

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