STAT2 Antibody

Signal transducer and activator of transcription 2 (STAT2) is a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P52630].
    Product/Catalog #SpecificationsPrice
    STAT2 Antibody
    A303-510A
    Reactivity: Human
    Applications: IP, IHC-P, IF
    $314.00
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    STAT2 Antibody
    A303-511A
    Reactivity: Human
    100% Sequence Identity:
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Data Sheet
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    STAT2 Antibody
    A303-512A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Data Sheet
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    STAT2 Antibody AbVantage™ Pack
    A311-294A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A303-510A, A303-511A and A303-512A
    $655.00
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