STAT2 Antibody

Signal transducer and activator of transcription 2 (STAT2) is a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P52630].
    Product Specifications
    Catalog # Size Price
    STAT2 AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 175 and 225
    A303-510A100 µl (1 mg/ml) $339Add to Cart
    A303-510A-T10 µl (1 mg/ml) $50Add to Cart
    STAT2 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 725 and 775
    A303-511A100 µl (0.2 mg/ml) $339Add to Cart
    A303-511A-M100 µl (10 blots) $229Add to Cart
    A303-511A-T20 µl (2 blots) $50Add to Cart
    STAT2 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 801 and 851
    A303-512A100 µl (0.2 mg/ml) $339Add to Cart
    A303-512A-M100 µl (10 blots) $229Add to Cart
    A303-512A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A303-510A, A303-511A and A303-512A
    A311-294A1 Pack $707Add to Cart

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