SMN1 Antibody

Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.
    Product Specifications
    Catalog # Size Price
    SMN1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 50 and 100
    A301-862A100 µl (1 mg/ml) $339Add to Cart
    A301-862A-T10 µl (1 mg/ml) $50Add to Cart
    SMN1 AntibodyReactivity: Human
    Applications: WB, IP, PLA
    Immunogen: Between 244 and 294
    A301-863A100 µl (1 mg/ml) $339Add to Cart
    A301-863A-M100 µl (10 blots) $229Add to Cart
    A301-863A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, PLA
    Reactivity: Human
    Includes: 1 each of A301-862A and A301-863A
    A310-663A1 Pack $472Add to Cart

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