SMG7 plays a role in the dephosphorylation of UPF1, an RNA-dependent ATPase and helicase critical to nonsense-mediated mRNA decay (NMD). It is a homolog of the C. elegans NMD factor Smg7 (suppressor with morphogenetic effect on genitalia protein 7). SMG7 functions as an adaptor to target protein phosphatase 2A to UPF1 for dephosphorylation of UPF1.
Alternative names for
SMG7 Antibody include Protein
SMG-7 homolog antibody,
EST1-like protein C antibody,
SMG7 nonsense mediated mRNA decay factor antibody,
ever shorter telomeres 1C antibody,
EST1 telomerase component homolog C antibody,
breast cancer-associated antigen SGA-56M antibody,
smg-7 homolog, nonsense mediated mRNA decay factor antibody.