SMG1 Antibody

SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the translation termination release factors eRF3, and eRF1. This complex has been termed SURF and associates with the exon junction complex (EJC) to function in the recognition of premature termination codons in aberrant RNAs to trigger NMD.
    Product/Catalog #SpecificationsPrice
    SMG1 Antibody
    A300-393A
    Reactivity: Human
    Applications: WB
    $314.00
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    SMG1 Antibody
    A300-394A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    SMG1 Antibody
    A301-535A
    Reactivity: Human
    Applications: WB, IP, PLA
    $314.00
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    SMG1 Antibody AbVantage™ Pack
    A310-108A
    Applications: WB, IP, PLA, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A300-393A, A300-394A and A301-535A
    $655.00
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    SMG1 IHC Antibody
    IHC-00052
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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