SMG1 Antibody

SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the translation termination release factors eRF3, and eRF1. This complex has been termed SURF and associates with the exon junction complex (EJC) to function in the recognition of premature termination codons in aberrant RNAs to trigger NMD.
    Product Specifications
    Catalog # Size Price
    SMG1 AntibodyReactivity: Human
    Applications: WB
    Immunogen: Between 1625 and 1675
    A300-393A100 µl (1 mg/ml) $339Add to Cart
    A300-393A-M100 µl (10 blots) $229Add to Cart
    A300-393A-T20 µl (2 blots) $50Add to Cart
    SMG1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 2925 and 2975
    A300-394A100 µl (1 mg/ml) $339Add to Cart
    SMG1 AntibodyReactivity: Human
    Applications: WB, IP, PLA
    Immunogen: Between 1250 and 1300
    A301-535A100 µl (1 mg/ml) $339Add to Cart
    SMG1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 2925 and 2975
    IHC-00052100 µl (50+ slides) $360Add to Cart
    IHC-00052-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, PLA, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A300-393A, A300-394A and A301-535A
    A310-108A1 Pack $707Add to Cart

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