The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCD2/BAF60B was isolated from a cDNA library in a search for proteins similar to mouse BAF60A which was identified as the paralog of the S. cerevisiae SWI/SNF component, SWP73.
Alternative names for
SMARCD2/BAF60b Antibody include SMARCD2/BAF60b SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 antibody, 60 kDa BRG-1/Brm-associated factor subunit B antibody, BRG1-associated factor 60B antibody, Rsc6p antibody, CRACD2 antibody, PRO2451 antibody.