SMARCD1/BAF60a Antibody

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCD1/BAF60a is subunit of the SWI/SNF complex that has been identified as a factor that interacts with nuclear receptors such as the vitamin D receptor and glucocorticoid receptor and a subset of Fos/Jun dimers. SMARCD1 has also been shown to interact with p53 and is suggested to be involved in the tumor suppressor activity of p53. From these findings it has been concluded that SMARCD1 functions as a direct link between transcription factors and SWI/SNF remodeling activity to regulate transcription.
    Product Specifications
    Catalog # Size Price
    SMARCD1/BAF60a AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    A301-594A100 µl (1 mg/ml) $339Add to Cart
    A301-594A-T10 µl (1 mg/ml) $50Add to Cart
    SMARCD1/BAF60a AntibodyReactivity: Human
    Applications: WB
    Immunogen: Between 250 and 300
    A301-595A100 µl (0.2 mg/ml) $339Add to Cart
    A301-595A-M100 µl (10 blots) $229Add to Cart
    A301-595A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-594A and A301-595A
    A310-565A1 Pack $472Add to Cart

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