SHARP Antibody

SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
Antibodies Manufactured onclick Site
We Make Every Antibody
We Sell.

Please note that Cookies and JavaScript are required for you to view this website.

Check if you have Cookies and JavaScript enabled in your browser