SHARP Antibody

SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
    Product Specifications
    Catalog # Size Price
    SHARP AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1350 and 1400
    A301-119A100 µl (1 mg/ml) $339Add to Cart
    A301-119A-T10 µl (1 mg/ml) $50Add to Cart
    SHARP AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 3375 and 3425
    A301-120A100 µl (1 mg/ml) $339Add to Cart
    A301-120A-T10 µl (1 mg/ml) $50Add to Cart

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