SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome [taken from NCBI Entrez Gene (GeneID: 23450)].
Alternative names for
SF3B3 Antibody include splicing factor 3B subunit 3 antibody, splicesome-associated protein 130 antibody, SAP 130 antibody, pre-mRNA-splicing factor SF3b 130 kDa subunit antibody, SF3b130 antibody, STAF130 antibody, SAP130 antibody, RSE1 antibody, KIAA0017 antibody.