SENP3 Antibody

Sentrin-specific protease 3 (SENP3) functions as a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates.SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability, and also deconjugates SUMO2 and SUMO3 from CDCA8. SENP3 can function as a redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. SENP3 is required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1 [taken from the Universal Protein Resource (UniProt) Q9H4L4].
    Product Specifications
    Catalog # Size Price
    SENP3 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1 and 50
    A303-139A100 µl (1 mg/ml) $339Add to Cart
    A303-139A-M100 µl (10 blots) $229Add to Cart
    A303-139A-T20 µl (2 blots) $50Add to Cart
    SENP3 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 275 and 325
    A303-140A100 µl (1 mg/ml) $339Add to Cart
    A303-140A-M100 µl (10 blots) $229Add to Cart
    A303-140A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A303-139A and A303-140A
    A311-160A1 Pack $472Add to Cart

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