Rictor Antibody

Rictor is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6R327].
    Product/Catalog #SpecificationsPrice
    Rictor Antibody
    A300-458A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    Rictor Antibody
    A300-459A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, F
    $314.00
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    Rictor Antibody
    A304-329A
    Host: Rabbit
    Conjugate: Unconjugated
    Quantity: 0.1 ml
    $314.00
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    Rictor Antibody
    S300-458
    Reactivity: Human
    Applications: IP
    $330.00
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    Rictor Antibody
    S300-459
    Reactivity: Human, Mouse
    Applications: IP
    $364.00
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    Rictor Monoclonal Antibody
    A500-002A
    Applications: WB, IP, IHC, ICC, PLA
    Reactivity: Human
    Quantity: 0.1 ml (10 -100 blots)
    $314.00
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    Rictor Antibody AbVantage™ Pack
    A310-130A
    Applications: WB, IP, IHC-P, IF, F
    Reactivity: Human, Mouse
    Quantity: 1 each of A300-458A, A300-459A and A304-329A
    $655.00
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    Rictor IHC Antibody
    IHC-00429
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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