Rictor Antibody

Rictor is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6R327].
    Product Specifications
    Catalog # Size Price
    Rictor AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1 and 50
    A300-458A100 µl (1 mg/ml) $339Add to Cart
    A300-458A-M100 µl (10 blots) $229Add to Cart
    A300-458A-T20 µl (2 blots) $50Add to Cart
    Rictor AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, F
    Immunogen: Between 1650 and C-term
    A300-459A100 µl (1 mg/ml) $339Add to Cart
    A300-459A-M100 µl (10 blots) $229Add to Cart
    A300-459A-T20 µl (2 blots) $50Add to Cart
    Rictor AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 1 to 50
    A304-329A100 µl (1 mg/ml) $339Add to Cart
    A304-329A-T10 µl (1 mg/ml) $50Add to Cart
    Reactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    S300-458100 µg $356Add to Cart
    Reactivity: Human, Mouse
    Applications: IP
    Immunogen: Between 1650 and C-term
    S300-459100 µg $364Add to Cart
    Rictor Monoclonal AntibodyApplications: WB, IP, IHC, ICC, PLA
    Reactivity: Human
    Immunogen: Between 1650 and C-term
    A500-002A0.1 ml (10 -100 blots) $339Add to Cart
    Rictor IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 1650 and C-term
    IHC-00429100 µl (50+ slides) $360Add to Cart
    IHC-00429-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF, F
    Reactivity: Human, Mouse
    Includes: 1 each of A300-458A, A300-459A and A304-329A
    A310-130A1 Pack $707Add to Cart

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