RPA70 Antibody

Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
    Product Specifications
    Catalog # Size Price
    RPA70 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF, PLA
    Immunogen: Between 350 and 400
    A300-241A100 µl (1 mg/ml) $339Add to Cart
    A300-241A-M100 µl (10 blots) $229Add to Cart
    A300-241A-T20 µl (2 blots) $50Add to Cart
    Out of stock - Expected Release early November 2015 (Updated 10/05/2015)
    RPA70 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 350 and 400
    IHC-00409100 µl (50+ slides) $360Add to Cart
    IHC-00409-T10 µl (5+ slides) $50Add to Cart

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