ROCK2 Antibody

Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.
    Product Specifications
    Catalog # Size Price
    ROCK2 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1 and 100
    A300-046A100 µl (1 mg/ml) $339Add to Cart
    ROCK2 AntibodyReactivity: Human
    Applications: WB, IP, PLA
    Immunogen: Between 1320 and C-term
    A300-047A100 µl (1 mg/ml) $339Add to Cart
    Applications: WB, IP, PLA
    Reactivity: Human
    Includes: 1 each of A300-046A and A300-047A
    A310-011A1 Pack $472Add to Cart

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