ROCK1 Antibody

Rho-associated protein kinase 1 (ROCK1), also known as Rho kinase beta, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK1 shares an overall 65% homology in amino acid sequence with ROCK2. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.
    Product Specifications
    Catalog # Size Price
    ROCK1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 400 and 450
    A300-455A100 µl (1 mg/ml) $339Add to Cart
    A300-455A-T10 µl (1 mg/ml) $50Add to Cart
    ROCK1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 550 and 600
    A300-456A100 µl (1 mg/ml) $339Add to Cart
    A300-456A-M100 µl (10 blots) $229Add to Cart
    A300-456A-T20 µl (2 blots) $50Add to Cart
    ROCK1 AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 1300 and C-term
    A300-457A100 µl (1 mg/ml) $339Add to Cart
    A300-457A-M100 µl (10 blots) $229Add to Cart
    A300-457A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human, Mouse
    Includes: 1 each of A300-455A, A300-456A, A300-457A
    A310-129A1 Pack $707Add to Cart

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