Ring finger protein 34 (RNF34) has E3 ubiquitin-protein ligase activity and has been found to regulate the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. RNF34 protects cells against apoptosis induced by TNF. RNF34 binds phosphatidylinositol-5-phosphate and phosphatidylinositol-3-phosphate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q969K3].
Alternative names for
RNF34 Antibody include Caspase regulator CARP1 antibody, Caspases-8 and -10-associated RING finger protein 1 antibody, CARP-1 antibody,FYVE-RING finger protein Momo antibody, human RING finger homologous to inhibitor of apoptosis protein antibody, hRFI antibody, RING finger protein 34 antibody, RING finger protein RIFF antibody.